Salicylazosulfapyridine Powder Active Pharmaceutical Ingredients Raw Materials CAS 599-79-1 CAS NO.599-79-1

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Min.Order: 10 Gram
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Product Details

Keywords

Salicylazosulfapyridine
599-79-1
steroids

Quick Details

ProName: Salicylazosulfapyridine Powder Active ...
CasNo: 599-79-1
Molecular Formula: C18H14N4O5S
Appearance: White or Almost White Crystalline Powd...
Application: Sulfasalazine is used in the treatment...
DeliveryTime: 3-7days after confirmation your paymen...
PackAge: aluminum bag
Port: shanghai port
ProductionCapacity: 3000 Kilogram/Month
Purity: 99%
Storage: Shading, confined preservation
Transportation: We use EMS,TNT,FEDEX,DHL four kinds of...
LimitNum: 10 Gram

Superiority

Wuhan Demeikai Biotechnology Co., Ltd, a leading manufacturer and supplier of fine chemicals in China, is located in Wuhan City Hubei Province. Our company's various chemical raw material products have stable and reliable quality, it is mainly sold to pharmacy company and health care company in abroad, like USA, Canada, UK, Brazil, Netherlands, Ireland, New Zealand, Austria, Australia and so on.

The products achieve the advanced standard of domestic market, most of which even reach the international standard and conform to the requirements of FCC, USP, EP and BP with high level research group, advanced apparatus and good scientific atmosphere which ensure the stable and reliable quality. Besides, the factory has a complete Q. A. & Q. C. System. We own authorized sets of analyzing instruments that have high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products.

Details

1.Basic Info.

Product Name: Salicylazosulfapyridine
Purity: 99%
CAS No.: 599-79-1

MolecularFormula:C18H14N4O5S

Molecular weight:398.4

Specification:CP/USP/EP

Melting point: 260-265 °C (dec.)(lit.)

Solubility: NH4OH 1M: 50 mg/ml, clear, red

Solubility inwater, at 25 C: <0.1 g/100 ml

Appearance: white powder

2.Product Description:

Sulfasalazine was developed in the 1950s specifically to treat rheumatoid arthritis. It was believed at the time that bacterial infections were the cause of rheumatoid arthritis. Sulfasalazine is a sulfa drug, a derivative of mesalazine, and is formed by combining sulfapyridineand salicylate with an azo bond. It may be abbreviated SSZ.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Medical uses

3.Product Applications:

See also Disease-modifying antirheumatic drugs for its role in rheumatoid arthritis

Sulfasalazine is used in the treatment of inflammatory bowel disease, including ulcerative colitis and Crohn's disease. It is also indicated for use in rheumatoid arthritis and used in other types of inflammatory arthritis (e.g. psoriatic arthritis) where it has a beneficial effect. It is often well tolerated compared to other DMARDs.

In clinical trials for the treatment of chronic alcoholics, sulfasalazine has been found to reverse the scarring associated with liver cirrhosis. A study at Newcastle University found that the drug may act to aid the healing of cirrhosis of the liver. Cells called myofibroblasts, which contribute to scar tissue in a diseased liver, also appear to secrete proteins that prevent the breakdown of the scar tissue. Sulfasalazine appears to retard this secretion.

It is usually not given to children under 2 years of age.

The use of sulfasalazine in inflammatory bowel disease has declined due mainly to the fact that it yields the metabolitesulfapyridine which gives rise to side-effects such as agranulocytosis and hypospermia. However, the other metabolite of sulfasalazine, 5-aminosalicyli

Wuhan Demeikai Biotechnology Co., Ltd