Wuhan Demeikai Biotechnology Co., Ltd

Wuhan Demeikai Biotechnology Co., Ltd

Country: China (Mainland)Business Type: Lab/Research institutions

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  • Mr.Kong

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Mr.Jack
Tel: 86-171-92727886
Mr.Sam
Tel: 15527406774
Mr.Kong
Tel: 13260607296
  • Fax: 86-027-50461101
  • Province/state: HUBEI
  • City: WUHAN
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High Purity Flmodafinil Idebenone CAS No.: 58186-27-9 *1

High Purity Flmodafinil Idebenone CAS No.: 58186-27-9 *1 CAS NO.58186-27-9

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  • FOB Price: USD: 0.50-1.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
  • Available Specifications:

    USP(1-100)KilogramUSP(100-1000)KilogramCP(1-100)Kilogram

  • Product Details

Keywords

  • 58186-27-9
  • High purity
  • Idebenone

Quick Details

  • ProName: High Purity Flmodafinil Idebenone C...
  • CasNo: 58186-27-9
  • Molecular Formula: C15H13F2NO3S
  • Appearance: White powder
  • Application: health
  • DeliveryTime: 3
  • PackAge: Drum
  • Port: SHANGHAI
  • ProductionCapacity: 3000 Kilogram/Day
  • Purity: 99.5%
  • Storage: Dry storage
  • Transportation: air transport /Ocean Shipping
  • LimitNum: 1 Kilogram
  • Related Substances: 《0.1%
  • Residue on Ignition: 《0.1%
  • Heavy Metal: 《0.1%
  • Valid Period: 《0.1%
  • monthly production: 20kg
  • Customs code: 29000000

Superiority


 
 

 

 


 
Our Advantage:
 
.high quality
.high purity 
.best price
.best service
.professional manufacturer
.loyal and honest supplier 
.fast response to customer immediately
 
1.We have stock so we can delivery quickly at the very day when receive the payment.
 
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
 
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
 
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
 
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
 
Superiority
 
1. rich experience.
 
our company is a professional production leading factory in china in pharmaceutical area of many years, our products have exported to germany, spain, uk, usa, australia, middle east, and so on other country, and we have got very good feedback from our customers, we had established long friendly relations of cooperation. high quality, best price!
 
2. great quality, purity and favourable.
 
all products are produced under gmp conditions according to standard operation procedure(sop), not from little underground labs or black markets, so the quality is guaranteed.
 
good quality is one of our secret success, welcome order the samples, moq just 10 grams.
 
3. safe and fast delivery.
 
we have warehouse in australia, canada and england, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse! so we can delivery quickly at the very day when receive the payment. and we offer melting powder into liquid service.
 
our logistics department delivery parcel within 12 hours after confirming payment.
 
99% customs clearance rate.we have rich experience in shipping parcel to usa, australia, uk,canada, brazil, russia, germany, poland, mexico, etc.
 
4. good after-sales service.
 
excllent customer service. any question or doubt would be solved immediately.
 
5. discreet packing methods. for your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels.
 
6. injectable steroid. we offer melting powder into liquid service.and ship the liquid in special bottles.
 
 

Details

 

        With the high quality products and service, DMK aims to solve the customers' purchasing troubles and ensure the high efficiency and stability of the customers' supply chain.The company provides small batches of goods for customers' diversified needs, and reduces the trial risks and costs.


 
CAS 58186-27-9 Pharmaceutical Raw Materials Idebenone For Cerebral Infarction
 
Name: Idebenone
Synonyms:4-dione,5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-5-cyclohexadiene-1;6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone;2-(10-Hydroxy-Decyl)-5,6-Dimethoxy-3-Methyl-[1,4]Benzoquinone;2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-cyclohexa-2,5-diene-1,4-dione;idebonone
CAS:58186-27-9
MF:C19H30O5
MW:338.44
Chemical Properties:Yellow-Orange Crystalline Solid
Usage:Cognition enhancer, nootropic.Ubiquinone derivative with protective effects against cerebral ischemia.
Biological Activity:Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo . Inhibits apoptosis of astrocytes via increased NGF production.
Mechanisms: Idebenone (particularly its reduced form) is highly antioxidative, with IC50 values against oxidative damage in the range of 0.5-10µM.
 
What is Idebenone  
 
Idebenone is a cure for brain function and metabolism and mental symptoms of novel anti Alzhei-mer's drug improvement.It can improve brain energy metabolism, improve brain function, and a mild antihypertensive effect. Clinic for cerebral infarction, cerebral hemorrhage and brain dysfunction caused by arteriosclerosis sequelae, low awareness , mood disorders, language disorders, dementia. This product is antioxidant. Idebenone is an existing product in the most effective topical antioxidant.
 
Description
 
Idebenone is an organic compound belonging to the quinone family, being similar to coenzyme Q-10. However, these have been not very much progress associated with this indication. It is now also used for the treatment of Friedreich's ataxia with a positive effect on cardiac hypertrophy and neurological function.
 
However, this indication is only approved in Canada, not in Europe and US. It is now under investigation on its efficacy for the treatment of Duchenne muscular dystrophy, Leber's hereditary optic neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) as well as primary progressive multiple sclerosis. The efficacy of this drug still demands more evidences.
 
Application
 
1) Memory and Learning
 
Impairments (via age or injury) in passive avoidance retention, working memory, and delayed alternation can be reduced or reversed by pretraining administration of 3-30mg/kg idebenone For acute usage, 30mg/kg appears to be optimal when injected (intraperitoneal) whereas 3mg/kg injections are sufficient for chronic studies.
 
2) Alzheimer's
 
Idebenone has been found to be neuroprotective against β-amyloid peptides which is thought to be related to the antioxidative properties of idebenone (as antioxidants, per se, are neuroprotective). These protective effects have been confirmed in vivo as assessed by a reduction in memory loss.
 
3) Glutaminergic Neurotransmission
 
In vitro, Idebenone can reduce glutamate-induced toxicity in the range of 0.1-3µM secondary to its antioxidative properties, and at a potency exceeding Vitamin E (requiring 10-100µM) and Vinpocetine (10-100µM). It also appears effective against excitotoxicity associated with ATP depletion (independent of NMDA receptors, but still from glutamate) secondary to its antioxidative effects.
 
Unlike many other compounds, Idebenone appears to be protective against excitotoxicity mediated via the AMPA and kainate receptors but not NMDA although some general neuroprotection from the antioxidative effects may persist on NMDA (as noted elsewhere).
 
Ischemia (damaging via glutamate) appears to be protected against with idebenone (100mg/kg intraperitoneal injections) and secondary to that a preservation of memory (losses seen with ischemic control).
     
 

 


 

Our Advantage:


1.We have stock so we can delivery quickly at the very day when receive the payment.

2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.

3.High quality guarenteed, once any problem is found, the package would be reshipped for you

4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.

5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.

Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express

FAQ

1.How about parcel delivery success rate

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.



 

Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express


FAQ

1.How about parcel delivery success rate

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship b

 
 

 
 

 


 
 
 
 
 
 
QAF
 
Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
 
Q2: How to start orders or make payments 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or MoneyGram or Escrow
 
Q3: How to confirm the Product Quality before placing orders 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q4:Is there a discount 
A:Different quantity has different discount.
 
Q5: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a 
real quality problem caused by us, we will send you free goods for replacement or refund your loss.
4.QAF
 
Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
 
Q2: How to start orders or make payments 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or MoneyGram or Escrow
 
Q3: How to confirm the Product Quality before placing orders 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q4:Is there a discount 
A:Different quantity has different discount.
 
Q5: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a 
real quality problem caused by us, we will send you free goods for replacement or refund your loss.
 
 

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