Wuhan Demeikai Biotechnology Co., Ltd

Wuhan Demeikai Biotechnology Co., Ltd

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Chemical Supplier Provide Dehydroisoandrosterone/1-DHEA Powder Function and Usage

Chemical Supplier Provide Dehydroisoandrosterone/1-DHEA Powder Function and Usage CAS NO.53-43-0

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  • FOB Price: USD: 0.50-1.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
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    USP(1-100)KilogramUSP(100-1000)KilogramCP(1-100)Kilogram

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Keywords

  • 1-DHEA
  • Dehydroisoandrosterone Powder
  • Steriod

Quick Details

  • ProName: Chemical Supplier Provide Dehydroisoan...
  • CasNo: 53-43-0
  • Molecular Formula: C21H30O3
  • Appearance: White powder
  • Application: Only for Research Use
  • DeliveryTime: 3
  • PackAge: Drum
  • Port: SHANGHAI
  • ProductionCapacity: 3000 Kilogram/Day
  • Purity: 99
  • Storage: Dry storage
  • Transportation: air transport /Ocean Shipping
  • LimitNum: 1 Kilogram
  • Related Substances: 《0.1%
  • Residue on Ignition: 《0.1%
  • Heavy Metal: 《0.1%
  • Valid Period: 《0.1%
  • monthly production: 20kg
  • Customs code: 29000000

Superiority

Dehydroisoandrosterone
Dehydroepiandrosteron Basic Info.
Product name : Dehydroepiandrosteron;1-DHEA
Other name :   Dehydroepiandrosteron acetate (DHA); 5-Epiandroster-17-one acetate ; DHE-A Acetate, 1-DHEA
CAS register number :   53-43-0
Molecular formula  :  C21H30O3
Molecular weight :   330.4611
Assay   : Above 99.3%
Usage  :  pharmaceutical material, Steroid hormone, Anabolin
 
Dehydroepiandrosterone Function:
Dehydroepiandrosterone (DHEA), also known as androstenolone or prasterone (INN), is an endogenous steroid hormone. It is the most abundant circulating steroid hormone in humans, in whom it is produced in the adrenal glands, the gonads, and the brain, where it functions predominantly as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids. However, DHEA also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid
DHEA is sometimes used as an androgen in hormone replacement therapy (HRT) for menopause. A long-lasting ester prodrug of DHEA, prasterone enanthate, is used in combination with estradiol valerate for this indication
 
1. Anti-aging, retain green vigor. 
2. Enhance physical fitness, improve mood and sleep, improve memory; 
3. Improve sexual function, improve sexual desire; 
4. Adjust the immune system function, improve body immunity, 
5. Weight loss; 
6. Assist to treat disease  
 
 
1-DHEA Dosage:
The dosing one chooses to work with varies greatly on whether they are stacking this compound with other anabolics or running it solo. Generally with 1-DHEA 300-600mg a day is the most popular dosage, however experienced users with past pro-hormone or designer steroid experience can experiment with dosages in upwards of 700-1000mg. The added benefit may be negligible at this dosage and the likely-hood of side effects sharply increases..
 
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length with 6 weeks being the most common. Most users will begin to notice the effects by the third week in the form of muscle hardness/increased strength. Novice users should always stay within the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced users can safely run 1-DHEA for 8 weeks.
 
You should split up your dosages into 2-3 different times throughout the day, ideally separated by 5-6 hours (or 8 hours if two daily dosages). For the ideal results, take your largest dosage 45 minutes to one hour before your workout session.

 

Details

Dehydroisoandrosterone
Dehydroepiandrosteron Basic Info.
Product name : Dehydroepiandrosteron;1-DHEA
Other name :   Dehydroepiandrosteron acetate (DHA); 5-Epiandroster-17-one acetate ; DHE-A Acetate, 1-DHEA
CAS register number :   53-43-0
Molecular formula  :  C21H30O3
Molecular weight :   330.4611
Assay   : Above 99.3%
Usage  :  pharmaceutical material, Steroid hormone, Anabolin
 
Dehydroepiandrosterone Function:
Dehydroepiandrosterone (DHEA), also known as androstenolone or prasterone (INN), is an endogenous steroid hormone. It is the most abundant circulating steroid hormone in humans, in whom it is produced in the adrenal glands, the gonads, and the brain, where it functions predominantly as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids. However, DHEA also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid
DHEA is sometimes used as an androgen in hormone replacement therapy (HRT) for menopause. A long-lasting ester prodrug of DHEA, prasterone enanthate, is used in combination with estradiol valerate for this indication
 
1. Anti-aging, retain green vigor. 
2. Enhance physical fitness, improve mood and sleep, improve memory; 
3. Improve sexual function, improve sexual desire; 
4. Adjust the immune system function, improve body immunity, 
5. Weight loss; 
6. Assist to treat disease  
 
 
1-DHEA Dosage:
The dosing one chooses to work with varies greatly on whether they are stacking this compound with other anabolics or running it solo. Generally with 1-DHEA 300-600mg a day is the most popular dosage, however experienced users with past pro-hormone or designer steroid experience can experiment with dosages in upwards of 700-1000mg. The added benefit may be negligible at this dosage and the likely-hood of side effects sharply increases..
 
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length with 6 weeks being the most common. Most users will begin to notice the effects by the third week in the form of muscle hardness/increased strength. Novice users should always stay within the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced users can safely run 1-DHEA for 8 weeks.
 
You should split up your dosages into 2-3 different times throughout the day, ideally separated by 5-6 hours (or 8 hours if two daily dosages). For the ideal results, take your largest dosage 45 minutes to one hour before your workout session.
 
 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
How to order
 
1. Let me know the products with quantity you are interesting and your requirement, you will get the best offer.
 
2. After we confirm all the details about the order, Products will send out within 24 hours after we received your payment(MoneyGram,,T/T is accepted).
 
3. Tracking No. will send to you within 2-3days.After 7days you will received your package.
 
4. We will take care of your order till parcel to your door, and expecting for your further feedback, 24 hours on line for after-sale service.
 
Wuhan Demeikai Biotechnology Co., Ltd is a legitimate companies which registration in the Trade and Industry Bureau.Main business:Research and development, production and sales of Steriods,Peptides,raw materials and intermediates.
The company has a legitimate import and export qualifications, and in the State Ministry of Commerce for the record registration, registration number 03027567.
 
We are the forefront of Chinese for the production and sales of raw materials business, the company is located in Wuhan University high-tech business incubator, relying on the "innovation" wave of national support program and having a reputation for goverment supporting plan.Owning a large number of outstanding scientific research talents and equipped with advanced production equipment and efficiently sophisticated detection equipment, setting up a strict and scientific quality management system, and continuously committed to technological innovation, product innovation and management innovation.
 
Company purpose:Quality is the foundation of development,always maintain a competitive price.
Hope to achieve mutually beneficial and win-win goal with our customers.
 
Our superiority
1. We has passed the ISO9001: 2000 (quality management system certification) ISO14001: 2004 (environmental management system certification), OHSMS (occupational health and safety system certification) three system certification, won the "Attaches great importance to contract, keep promise" and won Hubei Province Civilized units and many other honors. 
 
2.The company's large-scale, solid technical foundation, adequate supply,so that we can meet the different needs of various customers.
 
3. Professional sales team to meet the various needs of customers, customers timely answers to various questions,achieve good communication,ensure good after-sales service and solve your worries.
 
4.Improve the logistics system to ensure that customers will konw the movements of goods in the first time after the shipment.
 
5.To provide third-party product testing reports, integrity management.

 

 
Laxogenin (5a-Hydroxy) is an anabolic building block that is derived from plants, and it can be used by the body to create its own anabolics.  It does this by increasing protein synthesis and nitrogen retention, creating an anabolic environment in the body that gives the effects of increased muscle strength and mass, endurance, recovery, and lean gains.  What's more, laxogenin also inhibits cortisol - a nasty hormone we get from both mental and physical stress, which signals the body to store fat and burn muscle.
 
 
Interestingly, people may not be aware that laxogenin was studied by the Japanese as far back as the early 1960's, but it was not brought to the public attention until the 90's.  Since then, supplement companies have used this compound in their products in order to give athletes a boost.
 
Basic info of 5a-hydroxy laxogenin
Product Name: 5a-hydroxy laxogenin,Spirostan-6-one, 3,5-dihydroxy-, (3b,5a,25R)-
Synonyms: Spirostan-6-one, 3,5-dihydroxy-, (3b,5a,25R)-;5a-hydroxy laxogenin
MF: C27H42O5
MW: 446.619
CAS: 56786-63-1 
 
 
How 5a-hydroxy laxogenin works
 
Laxogenin was isolated in 1992 from rhizomes of smilax sieboldii (a plant species found throughout the world, but native to Asia).  It is considered to be a type of steroidal sapogenin, and part of a group called brassinosteroids, which are part of a group of 40 different steroids that are synthesized from species of plants.   Within the plant, these amazing compounds promote growth and vitality.
 
smilax sieboldii seeds
Fig 2. Smilax Sieboldii seeds
However, a study from the FASEB journal in 2010 showed that these brassinosteroids actually trigger anabolic effects by increasing protein synthesis, while halting protein breakdown.  As we all know, protein is the building block of muscle, but with laxogenin you also get such benefits as fat loss and performance enhancement.
 
As a matter of fact, laxogenin is known to be the only product available that can give you anabolic gains in mass and strength without the steroidal suppression, or other side effects.  Therefore, athletes can use it on a caloric restricted diet to prevent loss of muscle and strength.  Furthermore,  it will also help control glucose and increase thyroid function (metabolism).  Besides, according to one experiment from the late 80's in Japan, laxogenin has been shown to have anti inflammatory benefits and a prominent anti-tumor potential.
 
5a-hydroxy laxogenin Benefits
 
The benefits of laxogenin are not as strong as anabolic steroids, but they do have some advantages:
 
It will not show up on any narcotic, or anabolic, drug screens.  Tested athletes need not worry about being busted for this compound.
It has no effects on the HPTA (hypothalamus-pituitary-testicular axis) or estrogen levels, so it is not necessary to run a post cycle therapy (PCT) or use an aromatase inhibitor.  Meanwhile, anabolic steroids cause LH (luteinizing hormone) suppression of about 95%, and require a strong PCT for a proper recovery.
Results can be very fast with laxogenin, unlike some injectable steroids, which take time to give any considerable results.
Just like anabolic androgenic steroids, laxogenin also inhibits cortisol without other side effects.  Hence, it can prevent fat gain.
This compound increases protein synthesis by over 200%, giving you the advantages of steroid use, without the harsh side effects found with steroids.
It does not cause liver strain like oral anabolic steroids or pro-hormones do.
Laxogenin does not cause increases in DHT, which can fry your head hair follicles.  Thus, your hairline will stay intact.
 

 

Dutasteride Basic Info.
CAS: 164656-23-9
Assay: 99%
Packing: 25kg/drum
MF: C27H30F6N2O2
MW: 528.53
Appearance: White to light yellow crystalline powder
 
Dutasteride Applications :
Dutasteride (brand name Avodart), It is used to treat benign prostatic hyperplasia. It increases the risk of erectile dysfunction and decreased sexual desire.
Avodart (dutasteride) 500 µg soft capsules
Dutasteride is useful for treating benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate"
 
Dutasteride, with the IUPAC Name of (1S,3aS,3bS,5aR,9aR,11aS)-N-[2,5-bis(Trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide, is one kind of white crystalline solid. This chemical belongs to the Product Categories which include Miscellaneous Biochemicals; All Inhibitors; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids.
 
 
Uses of Dutasteride: Dutasteride can inhibits the conversion of testosterone into dihydrotestosterone (DHT). It is approved for the treatment of benign prostatic hyperplasia (BPH), besides it is prescibed off-label for the treatment of male pattern baldness (MPB).
********************************
Dutasteride is used for:
 
Treating symptoms of benign prostatic hyperplasia (BPH) or enlargement of the prostate gland. It also helps to reduce the risk of urinary blockage and the need for surgery to treat BPH. It may be used alone or along with another medicine (tamsulosin).
 
Dutasteride is a 5 alpha-reductase enzyme inhibitor. It works by lowering levels of a hormone called dihydrotestosterone (DHT), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland.
A man’s prostate continues to grow throughout his lifetime. For some men, their prostate becomes so large that it begins to cause problems. This is a condition called benign prostatic hyperplasia (BPH). BPH is more commonly know as enlarged prostate. This condition typically develops in older men. Men with BPH may have symptoms such as the need to urinate more often, difficulty starting a urine stream, or decreased urine flow.
 
Drugs that treat BPH belong to a class called 5alpha-reductase inhibitors. Dutasteride and finasteride are two popular 5alpha-reductase inhibitors that are used to treat BPH. These drugs prevent male hormones from increasing the size of your prostate. You generally need to have been taking one of these drugs for at least 6 months before your BPH symptoms improve.
 

 

Name: Tetracaine 
Other name:Amethocalne,Dlcalne,PONTOCAINE,PANTOCAINE,DECICAINE
CAS No.:94-24-6
MF: C15H24N2O2
MW: 264.36
EINECS: 202-316-6
storage temp. 2-8°C
Purity: 99%
Description : White crystal or crystalline powder
Package: 1KG foil bag; 25Kg drum
 
Description:
 
Tetracaine (also known as amethocaine; trade name Pontocaine and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
 
How it works:
 
Topical anesthetics stabilize the neuronal membrane and prevent the initiation and transmission of nerve impulses, thereby effecting local anesthesia. The onset of anesthesia usually begins within 30 seconds and lasts a relatively short period of time.
 
Application:
Tetracaine is a topical opththalmic anesthetic used to relieve the pain the skin and as an eye drops for minor eye operations. It prevents voltage-sensitive release of Ca2+ from sarcoplasmic reticulum and can be used as a spinal anesthetic.
 
Tetracaine is a local anesthetic (numbing medicine). It works by blocking nerve signals in your body.
 
Tetracaine topical (for the skin) is used to numb different parts of the body before a medical test or procedure.
 
Tetracaine topical may also be used for purposes not listed in this medication guide.
 

 

Idarubicin Basic Info.
 
Product Name: Idarubicin hydrochloride
Synonyms: IDARUBICIN HCL;IDARUBICIN HYDROCHLORIDE;4-demethoxy-daunomycihydrochloride;4-demethoxydaunorubicinhydrochloride;(7s-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione;4-DMD HCl;5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, hydrochloride, (7S,9S)-;5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, hydrochloride, (7S-cis)-
CAS: 57852-57-0
MF: C26H28ClNO9
MW: 533.95
EINECS: 260-990-7
Product Categories: API;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Idamycin, Zavedos, 4-demethoxydaunorubicin;Anti-cancer&immunity
Mol File: 57852-57-0.mol
Idarubicin hydrochloride Structure
Idarubicin hydrochloride Chemical Properties
mp: 183-185 C
storage temp.: 2-8°C
Safety Information
Hazard Codes: T+,Xn
Risk Statements: 60-61-28-40
Safety Statements: 53-45-36-22
RIDADR: UN 2811
RTECS: HB7877000
MSDS Information
Idarubicin hydrochloride Usage And Synthesis
Chemical Properties: Orange Solid
 
Idarubicin is used for:
Treating a certain type of cancer (acute myeloid leukemia [AML]). It may also be used for other conditions as determined by your doctor.
Idarubicin is a cytotoxic agent. It works by inhibiting activities of the cancer cell necessary for life and growth. This prevents the cancer cell from reproducing and results in death of the cancer cell.
 

 

Maytansine Basic Info.
Product name:maytansine
CAS:35846-53-8
Molecular Formula:C34H46ClN3O10
Formula Weight:692.201
Description:Maytansine (USAN), or maitansine (INN), is a cytotoxic agent. It inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
It is a macrolide of the ansamycin type and can be isolated from plants of the genus Maytenus.
 

 

PF06463922 Basic Info.
 
Synonyms: (10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
 
CAS:1454846-35-5, 
MF:C21H19FN6O2
MW:406.41
PF-06463922 is a novel, orally available, CNS-penetrant, ATP-competitive inhibitor of ALK/ROS1 with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively.
Usage:PF-06463922 demonstrates significant cell activity against ALK and a large set of ALK clinical mutations with IC50 ranging from 0.2 nM-77 nM. PF-06463922 exhibited subnanomolar cellular potency against oncogenic ROS1 fusions and inhibited the crizotinib-refractory ROS1(G2032R) mutation and the ROS1(G2026M) gatekeeper mutation. Compared with crizotinib and the second-generation ALK/ROS1 inhibitors ceritinib and alectinib, PF-06463922 showed significantly improved inhibitory activity against ROS1 kinase. in vivo: PF-06463922 showed marked antitumor activity in tumor models expressing FIG-ROS1, CD74-ROS1, and the CD74-ROS1(G2032R) mutation. Furthermore, PF-06463922 demonstrated antitumor activity in a genetically engineered mouse model of FIG-ROS1 glioblastoma.
 
PF-06463922 Application:
 
 PF-06463922 is the second generation of crizotinib,in total ALK inhibitors Divided into the third generation.
 The ALK Drug programs is crizotinib→AP26113,CH5424802,LDK378→PF06463922。
 
 The efficacy of PF-06463922 is crizotinib forty times,AP26113 six times.
 PF-06463922 can inhibit 9 mutation after resistant of crizotinib,AP26113 can inhibit two kinds,CH5424802  can inhibit three kinds,LDK378can inhibit four kinds,but AP26113 and LDK378 just like sister,as they have almost the same structure, mechanism of action.
 
 3922 using new big ring structure, action mechanism and the effect is greatly increased.
 
  PF-06463922 also can inhibition of ros1 targets.Its force is 3 times of alk, is currently ros1 second generation of medicine.
 

 

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