Wuhan Demeikai Biotechnology Co., Ltd

Wuhan Demeikai Biotechnology Co., Ltd

Country: China (Mainland)Business Type: Lab/Research institutions

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  • Mr.Kong

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Tel: 86-171-92727886
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Tel: 15527406774
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Tel: 13260607296
  • Fax: 86-027-50461101
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  • City: WUHAN
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High Quality and High Purity Pharmaceutical Raw Powder Levamisole HCl Anthelmintic Agent CAS 16595-80-5

High Quality and High Purity Pharmaceutical Raw Powder Levamisole HCl Anthelmintic Agent CAS 16595-80-5 CAS NO.16595-80-5

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  • FOB Price: USD: 0.50-1.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
  • Available Specifications:

    USP(1-100)KilogramUSP(100-1000)KilogramCP(1-100)Kilogram

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Keywords

  • 16595-80-5
  • High purity
  • Levamisole Hydrochloride

Quick Details

  • ProName: High Quality and High Purity Pharmaceu...
  • CasNo: 16595-80-5
  • Molecular Formula: C11H13ClN2S
  • Appearance: White powder
  • Application: health
  • DeliveryTime: 3
  • PackAge: Drum
  • Port: SHANGHAI
  • ProductionCapacity: 3000 Kilogram/Day
  • Purity: 99.5%
  • Storage: Dry storage
  • Transportation: air transport /Ocean Shipping
  • LimitNum: 1 Kilogram
  • Related Substances: 《0.1%
  • Residue on Ignition: 《0.1%
  • Heavy Metal: 《0.1%
  • Valid Period: 《0.1%
  • monthly production: 20kg
  • Customs code: 29000000

Superiority


 
 

 

 


 
Our Advantage:
 
.high quality
.high purity 
.best price
.best service
.professional manufacturer
.loyal and honest supplier 
.fast response to customer immediately
 
1.We have stock so we can delivery quickly at the very day when receive the payment.
 
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
 
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
 
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
 
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
 
Superiority
 
1. rich experience.
 
our company is a professional production leading factory in china in pharmaceutical area of many years, our products have exported to germany, spain, uk, usa, australia, middle east, and so on other country, and we have got very good feedback from our customers, we had established long friendly relations of cooperation. high quality, best price!
 
2. great quality, purity and favourable.
 
all products are produced under gmp conditions according to standard operation procedure(sop), not from little underground labs or black markets, so the quality is guaranteed.
 
good quality is one of our secret success, welcome order the samples, moq just 10 grams.
 
3. safe and fast delivery.
 
we have warehouse in australia, canada and england, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse! so we can delivery quickly at the very day when receive the payment. and we offer melting powder into liquid service.
 
our logistics department delivery parcel within 12 hours after confirming payment.
 
99% customs clearance rate.we have rich experience in shipping parcel to usa, australia, uk,canada, brazil, russia, germany, poland, mexico, etc.
 
4. good after-sales service.
 
excllent customer service. any question or doubt would be solved immediately.
 
5. discreet packing methods. for your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels.
 
6. injectable steroid. we offer melting powder into liquid service.and ship the liquid in special bottles.
 
 

Details

 

        With the high quality products and service, DMK aims to solve the customers' purchasing troubles and ensure the high efficiency and stability of the customers' supply chain.The company provides small batches of goods for customers' diversified needs, and reduces the trial risks and costs.


High Quality 99% Levamisole Hydrochloride with CAS 16595-80-5
 
Product Description
 
CAS: 16595-80-5
MF: C11H13ClN2S
MW: 240.75
EINECS: 240-654-6
Product Categories: API; Asymmetric Synthesis; Synthetic Organic Chemistry; Antibiotic Explorer; Veterinaries; Protein Phosphatase; Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Sulfur & Selenium Compounds; Pharma; Pharmaceutical intermediate; REZIFILM; Other APIs
Mol File: 16595-80-5. Mol
Synonyms: 1-b)thiazole, 2, 3, 5, 6-tetrahydro-6-phenyl-, monohydrochloride, (s)-imidazo(; 1-b)thiazole, 2, 3, 5, 6-tetrahydro-6-phenyl-, monohydrochloride, l-(-)-imidazo(; 1-b]thiazole, 2, 3, 5, 6-tetrahydro-6-phenyl-, monohydrochloride, (S)-Imidazo[2; Citarinl; Decaris; Imidazo[2, 1-b]thiazole, 2, 3, 5, 6-tetrahydro-6-phenyl-, monohydrochloride, (S)-; Kw-2-le-t; L-2, 3, 5, 6-Tetrahydro-6-phenylimidazo-[2, 1-6]-thiazole
 
Usage
 
Levamisole is also a good alternative in cases of benzimidazole resistance. Levamisole Hydrochloride (Levamisole HCl), is an anthelmintic (animals roundworm, hookworm, etc.) agent commonly used in large livestock such as cattle, pigs and sheep.
It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy. 
 
Description:
 
Levamisole Hydrochloride
Levamisole HCL
anthelmintic agent 
anti-worm agent used in large livestock
 
What is Levamisole Hydrochloride
 
Levamisole Hydrochloride (Levamisole HCL), is an anthelmintic (anti-worm) agent  commonly used in large livestock such as cattle, pigs and sheep. In 1971 it was found to have immunostimulatory properties and investigation into its use in humans began to expand.
 
Currently, Levamisole HCL is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer.
 
It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans.  Another interesting use of levamisole in humans is as a treatment for common warts (verruca vulgaris). 
 
News of its anthelmintic efficacy and immune system benefits has been known among aquatic hobbyists for years. The problem however, is that there is not much in the way of definitive information on its use and application in the hobby.
 
Anecdotal accounts of how it has worked for those 'outside the box' aquarists who first braved its use with fish, and accounts of personal experience with Levamisole in individual aquariums are helpful, but the 'your mileage may vary' factor is immense.
 
Word about its usefulness in treating internal parasites in the ornamental fish trade has spread, but information regarding its use is limited and sometimes conflicting.
 
From the information I have found thus far, Levamisole HCL is safe to use in aquaria and effective against many internal parasites, especially nematodes, when used in appropriate dosages. It does not harm the bio-filter, plants, invertebrates or uninfected fish.
 
As an added benefit, it boosts the immune competence of fish, humans, large animals, birds and some reptiles.
 
This article hopes to pull together what scientific information is available, a bunch of individual accounts, apply some common sense, and put together in one place a helpful guide to the use of Levamisole for treating aquarium fish. 
 
Levamisole Hydrochloride Chemical Composition
 
Molecular Formula:    C11H12N2S HCl
Molecular Weight:      240.75062
Mass of C11H12N2S:  204.28968
Mass of HCl:             36.46094
Specific gravity:       .69724
 
Levamisole Hydrochloride is the LEVO-rotatory form (left-handed) of tetramisol. The DEXTRO isomer (right-handed) contributes to the toxicity, but not the therapeutic effect so it has been removed in marketed preparations.
 
Levamisole HCL is light sensitive. Store product in tightly closed light resistant containers. Leave off tank lights when treating.
 
There is also a phosphate form of Levamisole.
 
Applications:
 
Levamisole Hydrochloride, is an anthelmintic agent commonly used in large livestock such as cattle, pigs and sheep. In 1971 it was found to have immunostimulatory properties and investigation into its use in humans began to expand. Currently, Levamisole HCL is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans. Another interesting use of levamisole in humans is as a treatment for common warts.
 
How does Levamisole HCL work
 
How does Levamisole HCL work as an antiparasitic agent
 
Levamisole HCL is absorbed through the gut, can also be absorbed through the skin and is distributed throughout the body. 
 
Levamisole affects the neurotransmitters and paralyzes the worm (spastic paralysis). The fish then passes the inactive worms. Good gravel vacuuming is advised after treatment to remove the paralyzed (but still live) worms. 
 
 It is not ovicidal, which means it will not affect eggs already present, but it will affect the larval stage of the worm. To ensure complete eradication of the parasite treat again after remaining eggs have hatched.
 
How does Levamisole HCL work as an immunomodulator
 
The mechanism of action for its immunostimulating effects are not well understood. It is believed that it restores cell-mediated immune function in peripheral T-lymphocytes and stimulates phagocytosis by monocytes. 
 
The drug appears to restore depressed immune function rather than to stimulate 
response to above-normal levels. There are multitudes of medical studies being done with its use in humans and animals, the goal being to attain understanding of its immunomodulating mechanism. The mechanism will be defined, with time. 
 
However, at the time of the writing of this article, there is no complete answer to this question. For us, it is enough to know that it does stimulate immune function in fish that are suffering due to parasites or 
disease.
 
。。。。。。。。。。。。。。。。。。。。。。。。。。。。。
 
Levamisole, marketed under the trade name Ergamisol, is a medication used to treat parasitic worm infections.It has also been studied as a method to stimulate the immune system as part of the treatment of cancer.Levamisole remains in veterinary use as a dewormer for livestock.
 
Levamisole Hydrochloride (Levamisole HCL), is an anthelmintic (anti-worm) agent commonly used in large livestock such as cattle, pigs and sheep. Currently, Levamisole HCL is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans.  Another interesting use of levamisole in humans is as a treatment for common warts (verruca vulgaris). 
 
News of its anthelmintic efficacy and immune system benefits has been known among aquatic hobbyists for years. The problem however, is that there is not much in the way of definitive information on its use and application in the hobby. Anecdotal accounts of how it has worked for those 'outside the box' aquarists who first braved its use with fish, and accounts of personal experience with Levamisole in individual aquariums are helpful, but the 'your mileage may vary' factor is immense. Word about its usefulness in treating internal parasites in the ornamental fish trade has spread, but information regarding its use is limited and sometimes conflicting. From the information I have found thus far, Levamisole HCL is safe to use in aquaria and effective against many internal parasites, especially nematodes, when used in appropriate dosages. It does not harm the bio-filter, plants, invertebrates or uninfected fish. As an added benefit, it boosts the immune competence of fish, humans, large animals, birds and some reptiles.
 
Pharmacodynamic
 
Properties Levamisole refers to Levo tetramisole, it is the Levo Isomer of tetramisole. It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy.
 
L-isomer is active against helminthes with 1-2 times higher active efficiency and lower toxic and side effects than tetramisole. It is a broad spectrum anthelmintic with a very good activity against roundworms, hookworms, whipworms, and strongyloises stercoralis. It is an immunomodulator and has effect on rheumatic disorders.
Levamisole is also a good alternative in cases of benzimidazole resistance.
 
Side Effect
 
The most serious side effect of levamisole is low white blood cells that leaves person vulnerable to infection. It belongs to the class of synthetic imidazothiazole derivatives.
 

 


 
 
 


 

Our Advantage:


1.We have stock so we can delivery quickly at the very day when receive the payment.

2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.

3.High quality guarenteed, once any problem is found, the package would be reshipped for you

4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.

5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.

Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express

FAQ

1.How about parcel delivery success rate

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.



 

Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express


FAQ

1.How about parcel delivery success rate

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship b

 
 

 
 

 


 
 
 
 
 
 
QAF
 
Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
 
Q2: How to start orders or make payments 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or MoneyGram or Escrow
 
Q3: How to confirm the Product Quality before placing orders 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q4:Is there a discount 
A:Different quantity has different discount.
 
Q5: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a 
real quality problem caused by us, we will send you free goods for replacement or refund your loss.
4.QAF
 
Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
 
Q2: How to start orders or make payments 
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or MoneyGram or Escrow
 
Q3: How to confirm the Product Quality before placing orders 
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q4:Is there a discount 
A:Different quantity has different discount.
 
Q5: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a 
real quality problem caused by us, we will send you free goods for replacement or refund your loss.
 
 

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