White Powder SR9011 CAS 1379686-29-9 Research Raw Chemical For Fitness CAS NO.1379686-29-9
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- Min.Order: 10 Gram
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USP(10-49)GramUSP(50-100)Gram
- Product Details
Keywords
- Sr9011
- Sarms
- steroids
Quick Details
- ProName: White Powder SR9011 CAS 1379686-29-9 R...
- CasNo: 1379686-29-9
- Molecular Formula: C23H31ClN4O3S
- Appearance: White or Almost White Crystalline Powd...
- Application: SR9011 is a potent and specific synthe...
- DeliveryTime: 3-7days after confirmation your paymen...
- PackAge: aluminum bag
- Port: shanghai port
- ProductionCapacity: 3000 Kilogram/Month
- Purity: 99%
- Storage: Shading, confined preservation
- Transportation: We use EMS,TNT,FEDEX,DHL four kinds of...
- LimitNum: 10 Gram
- Related Substances: meets the requirement.
- Residue on Ignition: +68°~+72°
- Heavy Metal: ≤0.1%
- Valid Period: 2years
Superiority
CAS Registry Number: 1379686-29-9
Molecular Formula: C23H31ClN4O3S
Molecular Weight:4 79.03524
Purity: 99%
Appearance: White cystalline powder
Sarms Sr9011 Description:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Sarms Sr9011 Usage:
A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.
Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,
in mice that kickstarts metabolism and results in increased muscle development.
Essentially, it's an exercise regime in a pill.
SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed [in]
animals [that] are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify
its metabolism.
Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance
Details
CAS Registry Number: 1379686-29-9
Molecular Formula: C23H31ClN4O3S
Molecular Weight:4 79.03524
Purity: 99%
Appearance: White cystalline powder
Sarms Sr9011 Description:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Sarms Sr9011 Usage:
A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.
Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,
in mice that kickstarts metabolism and results in increased muscle development.
Essentially, it's an exercise regime in a pill.
SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed [in]
animals [that] are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify
its metabolism.
Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance
Sarms Sr9011Application:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic